I am revisiting the research question once again, “Can alcohol consumption increase the risk of breast cancer in working class women? and the variables to explore are;

- ‘alcconsumption’- average alcohol consumption, adult (15+) per capita consumption in litres pure alcohol
- ‘breastcancerper100TH’- Number of new cases of breast cancer in 100,000 female residents during the certain year
- ‘femaleemployrate’- Percentage of female population, age above 15, that has been employed during the given year

From the research question, the dependent variable or the response or the outcome variable is breast cancer per 100^{th} women and the independent variables are alcohol consumption and female employ rate

Let us now look at the measures of center and spread of the aforementioned variables. This will help us to better understand our quantitative variables. In python, to measure the mean, median, mode, minimum and maximum value, standard deviation and percentiles of a quantitative variable can be computed using the describe() function as shown below

# using the describe function to get the standard deviation and other descriptive statistics of our variables desc1=data['breastcancerper100th'].describe() desc2=data['femaleemployrate'].describe() desc3=data['alcconsumption'].describe() print "\nBreast Cancer per 100th person\n", desc1 print "\nfemale employ rate\n", desc2 print "\nAlcohol consumption in litres\n", desc3

And the result will be

Breast Cancer per 100th person count 173.000000 mean 37.402890 std 22.697901 min 3.900000 25% 20.600000 50% 30.000000 75% 50.300000 max 101.100000

So, on an average there are 37 women per 100th in whom breast cancer is reported with a standard deviation of +- 22.

Similarly, I next find the mean and standard deviation of the variable, ‘femalemployrate’

female employ rate count 178.000000 mean 47.549438 std 14.625743 min 11.300000 25% 38.725000 50% 47.549999 75% 55.875000 max 83.300003

I can say that on an average there are 47% women employed in a given year with a deviation of +-15.

Finally, I find the mean and deviation of the variable, ‘alcconsumption’ given as

Alcohol consumption in litres count 187.000000 mean 6.689412 std 4.899617 min 0.030000 25% 2.625000 50% 5.920000 75% 9.925000 max 23.010000

This can be interpreted as among adults (15+) the average alcohol consumption in liters per capita income is 7 liters (rounding off) with a standard deviation of +-5 (rounding off).

Therefore the inference will be that in 47% *(+-15)* employed women in a given year the average alcohol consumption is 7 liters (+-5) per capita and the number of breast cancer cases reported on an average are 37 (+-22) per 100th female residents.

Another, alternative method of finding descriptive statistic for your variables is to use the describe() on the dataframe which in this case is called ‘data’ as given

data.describe()

I now provide the univariate data analysis of the individual variables

# Now plotting the univariate quantitative variables using the distribution plot sub5=sub4.copy() sns.distplot(sub5['alcconsumption'].dropna(),kde=True) plt.xlabel('Alcohol consumption in litres') plt.title('Breast cancer in working class women') plt.show() '''Note: Although there is no need to use the show() method for ipython notebook as %matplotlib inline does the trick but I am adding it here because matplotlib inline does not work for an IDE like Pycharm and for that i need to use plt.show'''

And the barchart is

Bar Chart 1: Alcohol consumption in liters

Notice, we have two peaks in bar chart 1. So it is a bimodal distribution which means that there are two distinct groups of data. The two groups are evident from the bar chart 1, where the first group (or the first peak) is centered at 5 liters of alcohol consumption and the second group (or the second peak) is centered at 35 liters of alcohol consumption

sns.distplot(sub5['breastcancerper100th'].dropna(),kde=True) plt.xlabel('Breast cancer per 100th women') plt.title('Breast cancer in working class women') plt.show()

And the barchart is

Bar Chart 2: Breast cancer per 100th women

Similarly, in bar chart 2, there are two peaks so it is a bimodal distribution where the first group is centered at 35 cases of new breast cancer reported and the second group is centered at 86 cases of new breast cancer reported.

sns.distplot(sub5['femaleemployrate'].dropna(),kde=True) plt.xlabel('Female employee rate') plt.title('Breast cancer in working class women') plt.show()

And the bar chart is

Bar Chart 3: Female Employed Rate above 15+ (in %age) in a given year

In bar chart 3 we see a unimodal distribution where there is one group with maximum number of 42.

Now that we have seen the individual variable visually, I will now come back to the research question to see if there is any relationship between the research questions. Recall, for this study the various hypotheses were;

H_{0 }(Null Hypothesis) = Breast cancer is not caused by alcohol consumption

H_{1 }(Alternative Hypothesis) = Alcohol consumption causes breast cancer

H_{2 }(Alternative Hypothesis) = Female employee are susceptible to increased risk of breast cancer.

So, let’s check if there is any relationship between the breast cancer and alcohol consumption.

Please note here that since all the variables of this study are quantitative in nature so I will be using the scatter plot to visualize them.

Note that a histogram is not a bar chart. Histograms are used to show distributions of variables while bar charts are used to compare variables. Histograms plot quantitative data with ranges of the data grouped into bins or intervals while bar charts plot categorical data. For Dell Statistica, you can take a look here for the graphical data visualization and in Python it can be done using matplotlib library as shown here and a good SO question here

- When visualizing a categorical to categorical relationship we use a Bar Chart.
- When visualizing a categorical to quantitative relationship we use a Bar Chart.
- When visualizing a quantitative to quantitative relationship we use a Scatter Plot.

Also, please note that it is very important to bear in mind when plotting association between two variables, the independent or the explanatory variable is ‘X’ plotted on the x-axis and the dependent or the response variable is ‘Y’ plotted on the y-axis

So to check if the relationship exist or not, I code it in python as follows

# using scatter plot the visulaize quantitative variable. # if categorical variable then use histogram scat1= sns.regplot(x='alcconsumption', y='breastcancerper100th', data=data) plt.xlabel('Alcohol consumption in liters') plt.ylabel('Breast cancer per 100th person') plt.title('Scatterplot for the Association between Alcohol Consumption and Breast Cancer 100th person')

And the corresponding scatter plot is

Scatter Plot 1

From the scatter plot 1, its evident that we have a positive relationship between the two variables. And this proves the alternative hypothesis (H_{1}) that higher alcohol consumption by women has increased chances of breast cancer in them. Thus we can safely reject the null hypothesis that alcohol consumption does not cause breast cancer in women. Also, the points on the scatter plot are densely scattered around the linear line therefore the strength of the relationship is strong. This means that we have a statistically significant and strong positive relationship between higher alcohol consumption causing increased number of breast cancer patients in women.

Now, let us check if the other alternative hypothesis (H_{2}), “Female employee are susceptible to increased risk of breast cancer” is true or not. To verify this claim, I code it as

scat2= sns.regplot(x='femaleemployrate', y='breastcancerper100th', data=data) plt.xlabel('Female Employ Rate') plt.ylabel('Breast cancer per 100th person') plt.title('Scatterplot for the Association between Female Employ Rate and Breast Cancer per 100th Rate')

And the scatter plot is

Scatter Plot 2

From scatter plot 2, we can see that there is a negative relationship between the two variables. That means as the number of female employment count increases the number of breast cancer patients in employed women decreases. Also the strength of this relationship is weak as the number of points are sparsely located on the linear line. So, I will say that although the relationship is statistically significant but it is weak thus its safe to conclude that female employment rate does not necessarily contribute to breast cancer in women.

I now come to the conclusion of this analytical series. After performing descriptive and exploratory data analysis on the gapminder dataset using python as a programming tool, I have been successful in determining that higher alcohol consumption by women increases the chance of breast cancer in them. I have also been successful in determining that breast cancer occurrence in employed females has a weak correlation. Perhaps, there are other factors that could prove this.

Finally, to conclude this exploratory data analysis series of posts has been very fruitful and immensely captivating to me. In the next post, I will discuss on the statistical relationships between the variables and testing the hypotheses in the context of Analysis of Variance (when you have one quantitative variable and one categorical variable). And since the dataset that I chose does not have any categorical variable, I will also show how to categorize a quantitative variable.

I hope you enjoyed reading it as much as I enjoyed writing and presenting the results to you. The complete python code is listed on my GitHub account here

Thank you for reading.

Cheers

Ashish